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A 55 YEAR OLD FEMALE WITH FEVER, NECK STIFFNESS AND HEADACHE

FINAL PRACTICAL- SHORT CASE

HT NO: 1701006192

A 55 yr old female who is house maid by occupation came with chief complaints of

  • Head ache since 20 days
  • Fever since 5 days
  • Neck stiffness since 5 days

HISTORY OF PRESENTING ILLNESS:

     Patient was apparently asymptomatic 20 days back then she developed headache which was insidious onset, gradually progressive, not relieved on medications ,the headache aggravated 5 days back In spite of taking medication. No aggravating factors

Fever which was insidious onset since,intermittent,not relieved on medication.Not associated with chills / rigors,associated with neck stiffness 

One episode of vomiting food particles 3 days ago,non projectile, non bilious, , non blood stained.

No h/o of cold and cough 

No h/o of loose stools 

No h/o of abdominal pain

No h/o of breathlessness, PND , orthopnoea

No h/o of burning micturition, increased frequency of micturition. 


PAST HISTORY:

No history of similar complaints in the past.

7 yrs back she gave history of CVA due to which both upper and lower limbs were paralysed,she took allopathy medicine for 6 months and recovered.

Denovo detected diabetes

Not a known case of Hypertension, Asthma, Epilepsy,

Hysterectomy done at 25 yrs of age.

PERSONAL HISTORY:

Diet: Mixed

Appetite: Normal

Sleep: Adequate 

Bowel and bladder: Regular 

No addictions 

No known allergies

FAMILY HISTORY: Insignificant 

GENERAL EXAMINATION:

The patient was examined in a well lit room, with prior informed consent.

Patient is conscious, coherent, cooperative and is moderately built and malnourished 

No signs of Pallor , Icterus ,Cyanosis ,Clubbing , Lymphadenopathy and  Edema

VITALS :

Afebrile

Pulse rate : 75 bpm

Respiratory rate : 15 cpm 

Blood pressure : 120/70 mm of Hg 

SYSTEMIC EXAMINATION:

CNS EXAMINATION:

Higher mental functions:

-Patient is conscious, oriented to time and place 

-Memory is intact

-Speech and language normal

 

Cranial nerve examination

2 nd cranial nerve : Visual acuity - counting fingers from 6m distance 

3,4,6 cranial nerves : extraocular movements present, direct indirect reflexes present. 

5 th cranial nerve : sensations over face present 

7 th cranial nerve : forehead wrinkling present, able to blow cheek, able to open and close eyes, Naso labial folds normal 

8 th cranial nerve : hearing normal, no Nystagmus. 

9, 10 th cranial nerve : uvula centrally placed and symmetrical. 

11 th cranial nerve : trapezius and sternocleidomastoid normal 

12 th cranial nerve : tongue no deviation.

Motor examination:

                                                    

1.Bulk  

Inspection and palpation normal  

     Right Left 

   - MUAC 28 cm 27.5cm 

   - mid forearm 20 cm 20 cm

   - mid thigh 29 cm 30 cm

   - mid calf 25 cm 25 cm 

     

2. Tone 

 - upper limb normal normal 

 - Lower limb normal normal 


3.Power 

- upper limb 5/5 5/5 

- Lower limb 5/5 5/5     


4.Reflexes

 - knee jerk + +

 - Ankle jerk + +

 - Biceps + + 

 - triceps + +

 - Plantar - normal 








Meningeal signs:

1. Nuchal rigidity : present 

2. Kernig sign : positive 

3. Brudzinski sign : positive  


Sensory examination:Normal

Cerebellar examination : Normal


RESPIRATORY EXAMINATION:

Bilateral air entry present 

Normal vesicular breath sounds heard 


CVS EXAMINATION:

S1 and S2 heard 

No murmurs 


ABDOMINAL EXAMINATION:

Soft, non tender abdomen 

No organomegaly 

INVESTIGATIONS:

Hemogram 

Dengue NS1 antigen


CSF analysis


Glucose  : 81

Protein : 12.6


Arterial blood gas analysis : 

PH : 7.4

PCo2 : 29.1

PO2 : 88.4

HCO3 : 18

Fasting blood sugar - 168 mg/dl  

Complete urine examination : 

Albumin : positive 

Sugar : nil 

Pus cells : 6-8

Epithelial cells : 3-4

RBC and casts : nil 

RFT:

AST : 69 IU/L

ALT : 68 IU/L

ALP : 135 IU/L

Total protein : 6.4 gm/dl

Albumin : 4.0 gm/dl

Urea : 38 mg/dl

Creatinine : 1.0 mg/dl

Uric acid : 4.9 mg /dl


Serology : Non reactive 

X- ray neck:



MRI - FLAIR: Enhancements seen in leptomeninges and sulcal spaces in bilateral parietal and occipital areas, most likey meningitis.


PROVISIONAL DIAGNOSIS: 

Dengue fever with meningoencephalitis 


TREATMENT 

9 th and 10 th June 2022 :      

Injection ceftriaxone 2 gm / ml BD 

Injection dexamethasone 6 mg intravenous TID

Injection vancomycin 1 gm intravenous sos

Injection paracetamol 1 gm intravenous TID

Tab ecosporin 7 mg per oral OD 

Tab cremaffin 30 peroral 


INVESTIGATIONS ON DAY 2:

Hemogram

Hb- 13.1

Tlc-16,400 /mm3 

Neutrophils- 82

Leukocytes -9

Eosinophil -1

Monocyte -8

Platelet count -1.81lakh/mm3 


Arterial blood gas analysis : 

PH - 7.44

PCO2 - 28 

PO2 - 49.3

HCO3-18.7

O2 sat - 85.1

TREATMENT

Intravenous fluids NS and RL 

Injection ceftriaxone 2 gm / ml BD 

Injection dexamethasone 6 mg intravenous TID

Injection vancomycin 1 gm intravenous sos

Injection paracetamol 1 gm intravenous SOS

Tab paracetamol 650 mg TID

Tab ecosporin 7 mg per oral OD 

Tab cremaffin 30 peroral 

Tab metformin 500 mg per oral 



 

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