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A 63 YEAR OLD MALE WITH ANASARCA AND SOB

I've been given this case to solve in an attempt to understand the topic of "patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan.

A 63 year old male came to the casuality with the chief complaints of pedal edema since 4 days and facial puffiness since 2 days. He also complained of shortness of breath, decreased urine output and  decreased appetite since two days

HISTORY OF PRESENTING ILLNESS:

Patient was apparently asymptomatic four days ago when he developed facial puffiness which was sudden in onset and was gradually progressive. 

Patient also developed pedal edema of pitting type ,2 years ago which was insidious in onset and was persistent ,but gradually progressed to the present state four days ago. 

Patient also complains of SOB which was insidious in onset, gradually progressed from grade 2 to grade 3 NYHA.

No history of orthopnoea and PND.

PAST HISTORY:

Patient has a history of right sided hemiparesis secondary to CVA. It was treated conservatively with antiplatelet drugs which he was using on and off. He was able to walk after the treatment. 

He is also a k/c/o Hypertension since 1 1/2 year for which he is on regular medication ( Tab. Met XL )

He is also a k/c/o Diabetes since three years for which he's on Human Actrapid 15U--×--8U.

He is also a k/c/ o CKD 1 year ago for which he was managed conservatively and was not on hemodialysis.

He is also a k/ c/ o CAD since one year.

Not a k/c/o TB, Asthma ,epilepsy.

PERSONAL HISTORY:

Apetite: decreased

Diet: mixed

Sleep: Inadequate

Urine output: decreased

Constipation is present

Addictions: Patient was an alcoholic. Stopped alcohol 2 years ago.

No known allergies.

PHYSICAL EXAMINATION:

General examination

Consent was taken. Patient was examined in well-lit room. Patient has altered sensorium.

He is afebrile.

BP : 160/90 mm of Hg

Pulse rate : 97 bpm

Respiratory rate: 26 cpm

SpO2: 98%

He has pallor. 

Edema : present ( Anasarca)






Icterus, Clubbing, Cyanosis, Kolionychia Lymphadenopathy - absent.

SYSTEMIC EXAMINATION

CVS : S1 S2 heard (muffled)

Diffuse apex beat. 

No murmurs or thrills heard.

Respiratory system :

BAE+ , decreased B/L breath sounds.

B/L Crepts were heard. 

Dyspnoea of grade III

PER ABDOMEN:

Distended, Soft, non tender

Free fluid + 

Scrotal swelling is present.

CNS:

No abnormalities detected.

INVESTIGATIONS:

ECG


Hemogram:

Hb-9.4

TLC- 6000

PLC- 2.09 lakhs 

CUE:

Alb- +++

Sug- trace 

PC- 3-5

EC- 2-4


RBS- 184 mg/dl

HbA1C- 6.7 %


Urea-139

Creat-5.3

Uric acid-5.8

Na-141

K-5.6

Cl-101


TB- 0.94

DB- 0.13

AST- 10 

ALT- 09

ALP- 308

TP-5.1

Alb- 2.5

A/G- 1.02 


ABG:

PH- 7.124

pCo2- 29.4

PO2- 116

HCO3- 9.3

Spot Urine protein creat ratio- 4.97

Urinary Na- 198

Urinary K- 16.5

Urinary Cl- 409

-HIV, HbSAg, HCV, RAT for COVID 19- negative 

X Ray chest:


Rt sided pleural effusion with consolidation.

2D echo:

Global hypokinesia 

EF- 32%

Severe LV dysfunction 

Dilated all chambers 

IVC dilated ( 2.25 cms )

USG :

RT gross pleural effusion 

Lt moderate pleural effusion 

Gall bladder sludge +

B/L grade II RPD

Moderate ascites.

Diagnosis:

Acute LVF ( secondary to HTN) on chronic heart failure ( secondary to CAD) with right sided pleural effusion.

K/c/o Chronic kidney disease

K/c/o DM, HTN, CAD.

Treatment:

Fluid restriction 

Inj Lasix 40 mg / IV / Stat followed by inj Lasix 20 mg @ 2.5 ml / hr

Inj Pantop 40 mg IV/OD

Inj Zofer 4 mg IV/SOS 

Nebulisation with duolin and budecort 8th hourly 

Tab Ecosprin AV ( 75/ 20 ) PO/ H/S

Tab Amlong 10 mg PO/ H/S

Inj HAI S/C pre meal acc to sliding scale 

Vitals monitoring 2- hourly

GRBS monitoring 4th hourly

Weight monitoring daily 

Foleys catherisation done 

Pleural tap done I/v/o Rt sided gross pleural effusion - 1000 ml was tapped


Pleural fluid analysis:

Sugar- 198

Protein- 0.7

LDH- 154

Transudative pleural effusion.

Post pleural tap X- ray.


Plan - Hemodialysis in view of Severe metabolic acidosis 

And hyperkalemia ( serum K -6 )

Hemodialysis was done for 3 hours on 9/11/21 and 10/11/21

Ultrafiltrate removed- 500 ml

On 11/11/ 12 

SOB and edema decreased.

Pt is c/c/c




Temp-99.0F

Bp: 130/80 mmhg 

PR: 96 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA,ISA.

P/A: soft,non tender

GRBS: 158 mg/dl

I/O: 700ml/500 ml

SPO2: 98% @ RA

CNS: HMF INTACT

ABG:

PH: 7.278

PCO2: 39.1

PO2: 70.0

HCO3: 17.7


HEMOGRAM:

HB: 7.5

TC: 6,100

PLT: 1.5 lakhs

RFT:

UREA: 73

CREATININE: 3.3

UA: 3.6

Ca: 7.6

Po4: 3.4

Na: 148

K: 4.0

Cl: 101

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 2 years

DM since 2 yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)

with REFRACTORY HYPERKALEMIA ( RESOLVING).

With ANEMIA 

Plan:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

   8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal PO/OD


AMC bed 7, Unit 1

63/M

Day 5( 12/11/21)

S:

SOB decreased

EDEMA decreased

No fever spikes.

(2 sessions of hemodialysis done )


O:

Pt is c/c/c

Temp-97.6F

Bp: 110/90 mmhg 

PR: 82 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA. Coarse crepts + in RT ISA and MSA

P/A: soft,non tender

GRBS: 110 mg/dl

I/O: 900ml/550 ml

SPO2: 98% @ 4L O2

CNS: HMF INTACT


ABG:

PH: 7.323

PCO2: 38.3

PO2: 85.8

HCO3: 19



A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)

with REFRACTORY HYPERKALEMIA ( RESOLVING).

With ANEMIA 

P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal 500 mg PO/OD


AMC bed 7, Unit 1

65/M

Day 6 ( 13/11/12)

S:

Facial puffiness +

Pedal edema +

SOB decreased

No fever spikes.


2 sessions of hemodialysis done 

O:

Pt is c/c/c

Temp-98.4F

Bp: 130/70 mmhg 

PR: 98 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and ISA

P/A: soft,non tender

GRBS: 164 mg/dl

I/O: 800ml/950ml

SPO2: 98% @ 4L O2

CNS: HMF INTACT


ABG:

PH: 7.285

PCO2: 43.3

PO2: 127

HCO3: 19.9

HEMOGRAM 

Hb-7.0

TLC-5,700

PLC-1.5 lakhs 

RFT :

Urea-97

Creat -4.1

UA-4.7

CA-8.0

PO4-3.8

Na-148

K-4.1

Cl-103 



A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)

With REFRACTORY HYPERKALEMIA ( RESOLVED)

With ANEMIA 

P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

     8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

Tab Shelcal PO/OD

Plan for hemodialysis with PRBC transfusion


AMC bed 7, Unit 1

65/M

Day 7


S:

Pedal edema +

Facial puffiness+

(decreased since yesterday) 

SOB decreased

No fever spikes.

 1 session of hemodialysis along with PRBC transfusion done yesterday.

Total 3 sessions of hemodialysis done 


O:

Pt is c/c/c

Temp-97.7F

Bp: 110/80 mmhg 

PR: 99 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and ISA

P/A: soft,non tender

GRBS: 166 mg/dl

I/O: 1100ml /1000ml

SPO2: 99% @ RA

CNS: HMF INTACT

ABG:

PH: 7.26

PCO2: 56.4

PO2: 78.2

HCO3: 24.7


HEMOGRAM 

Hb-8.7

TLC-5,500

PLC-1.34 lakhs 


 RFT 

Urea-55

Creat -2.8

UA-3.3

Ca-9.8

PO4-3.0

Na-148

K-4.0

Cl-99

A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).


with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)

with REFRACTORY HYPERKALEMIA ( RESOLVED)

With ANEMIA 


P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD


AMC bed 7, Unit 1

65/M

Day 8

S:

Pedal edema +

Facial puffiness decreased 

SOB decreased
No fever spikes.

3 sessions of hemodialysis and 1 PRBC transfusion done

O:

Pt is c/c/c

Temp-98.6F

Bp: 110/70 mmhg 

PR: 86 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and SSA

P/A: soft,non tender

GRBS: 155 mg/dl

I/O: 600 ml/ 800 ml

SPO2: 99% @ 4L O2

CNS: HMF INTACT



ABG: report pending 

HEMOGRAM 

Hb-7.4

TLC-4,900

PLC-1.25 lakhs 



 RFT 

Urea-53

Creat -2.8

UA-3.0

Ca-8.2

PO4-2.3

Na-149

K-3.3

Cl-105

A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)

with REFRACTORY HYPERKALEMIA ( RESOLVED)

With ANEMIA 


P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

AMC bed 7, Unit 1

65/M

Day 10

S:

Pedal edema +

Facial puffiness decreased 

SOB decreased

No fever spikes.

4 sessions of hemodialysis and 2 PRBC transfusions done

O:

Pt is c/c/c

Temp-98.6F

Bp: 110/70 mmhg 

PR: 89 Bpm regular, normal volume.

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and SSA

P/A: soft,non tender

GRBS: 146 mg/dl

I/O: 950 ml/ 500 ml

SPO2: 99% @ 4L O2

CNS: HMF INTACT


ABG: 

pH - 7.45

pCO2 - 27.7

pO2 - 48.1

HEMOGRAM : report pending

RFT :

Urea-64

Creat -3.0

UA-3.0

Ca-8.7

PO4-2.8

Na-146

K-3.3

Cl-102

A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).
with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVING)

with REFRACTORY HYPERKALEMIA ( RESOLVED)

With ANEMIA 

P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM

Inj. Iron sucrose 1amp in 100ml

Inj Erythropoietin SC/ weekly once 

Nebulisation with duolin and budecort

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Tab Metolazone 10 mg PO/BD

AMC bed 7, Unit 1

65/M

Day 11



S:

B/L Pedal edema +

Facial puffiness decreased 

SOB decreased

No fever spikes.

 

4 sessions of hemodialysis and 2 PRBC transfusions done





O:

Pt is c/c/c

Temp-98.6F

Bp: 110/70 mmhg 

PR: 90 Bpm regular, normal volume.

RR: 20CPM

CVS: S1S2+, no murmers.

RS: NVBS+ , DECREASED BREATHSOUNDS IN RT IAA and SSA

P/A: soft,non tender

GRBS: 268 mg/dl

I/O: 800/200ML

SPO2: 99% @ 4L O2

CNS: HMF INTACT





HEMOGRAM : report pending



 RFT 

Urea-87

Creat -3.0

UA-3.3

Ca-8.4

PO4-2.3

Na-149

K-3.3

Cl-107


A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVED)

with REFRACTORY HYPERKALEMIA with k/c/o DM/HTN/CKD/CAD

P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj.pan 40mg/iv/OD

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM.

Nebulisation with duolin and budecort 8th hrly

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Weight monitoring daily.

Vitals monitoring daily.


AMC bed 7, Unit 1

65/M

Day 12

S:

B/L Pedal edema decreased.

Facial puffiness decreased 

SOB decreased

No fever spikes.

4 sessions of hemodialysis and 2 PRBC transfusions done

O:

Pt is c/c/c

Temp-98.6F

Bp: 110/70 mmhg 

PR: 92 Bpm regular, normal volume.

RR: 20CPM

CVS: S1S2+, no murmers.
RS: NVBS+ , B/L CREPTS IN RT IAA and ISA

P/A: soft,non tender

GRBS: 145 mg/dl

I/O: 750/300ML

SPO2: 98% @ 4L O2

CNS: HMF INTACT


HEMOGRAM

HB:7.8

PLT:2LAKH

TC: 14000



 RFT 

Urea-122

Creat -5.1

UA-4.4

Ca-8.0

PO4- 3.4

Na-140

K-4.5

Cl-107



ABG:

PH: 7.11

PCO2: 63.6

PO2: 35.3

HCO3: 19.4

ST.HCO3: 16.3

O2 SAT: 52.7

A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)


With REFRACTORY METABOLIC ACIDOSIS ( RESOLVED)

with REFRACTORY HYPERKALEMIA with k/c/o DM/HTN/CKD/CAD

P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj.pan 40mg/iv/OD

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM.

Nebulisation with duolin and budecort 8th hrly

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Weight monitoring daily.

Vitals monitoring daily.

PLANNING FOR DISCHARGE AND RE ADMIT

Day 13:

ICU BED 1-65/M

S-
c/o nausea, decreased intake of food since one day,
  sob +even after dialysis,orthopnea+ pt is preferring to sit most of the time.

facial puffiness and pedal edema decreased after dialysis.

O:
one session of haemodialysis done yesterday with one unit prbc transfusion

with UF-1500ml

pre dialysis weight:62kgs

post dialysis weight:55kgs

(total no. of dialysis :5 ,with 3 prbc transfused so far).

Pt is c/c/c :two fever spike after dialysis at 101.2F

Temp-afebrile

Bp: 100/60mmhg

PR: 98/min

RR: 24/min

CVS: S1S2+, no murmers.

RS: bae+ b/l infrascapular end insp coarse crepts+

P/A: soft,non tender

GRBS: 161mg/dl

SPO2:94%with 4lit o2

CNS: HMF INTACT

I/O:500/500ml ,only 50 ml since last night after dialysis

A:

ACUTE LVF ( secondary to HTN) ON CHRONIC HEART FAILURE (secondary to CAD).

with k/c/o CVA,CKD since 1yr

HTN since 1 and half yr

DM since 3yrs

With RIGHT SIDED PLEURAL EFFUSION ( TRANSUDATIVE)

With REFRACTORY METABOLIC ACIDOSIS ( RESOLVED)

P:

Salt restriction < 2.4 gm/day

fluid restriction < 1lit/day

Inj.pan 40mg/iv/OD

Inj. Lasix 40mg/i.v / TID

Inj.HAI PRE MEAL 

       8AM - 2PM - 8PM.

Nebulisation with duolin and budecort 8th hrly

Tab Amlong 10 mg PO H/S

Tab Ecosprin AV ( 75/20) PO/H/S

Tab Met XL 50 mg PO/OD

Weight monitoring daily.

Vitals monitoring daily.



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67 YEAR OLD MALE WITH SOB AND PEDAL EDEMA

Daily routine: He is a farmer by occupation. Resident of Miryalagudem Stopped working 2 years ago due to right femur fracture and old age. Wakes up at around 7:00 am in the morning. Eats breakfast by 8:00 am. Goes to his farm and monitors work. Then comes back to his house in the afternoon and has lunch by 1:00 pm. Sleeps for a while in the afternoon  He has a cup of tea in the evening at around 5:00 pm , watches TV for a while and has dinner at around 8:00 pm and goes to bed at around 9:30 pm. Chief complaints: Patient was brought to casualty with c/o shortness of breath Grade III MMRC since 20 days HOPI Patient was apparently asymptomatic 1 year ago when he developed angina and SOB Grade III and went to a hospital in Hyderabad  where he was diagnosed with CAD-evolved IWMI MOD LV DYSFUNCTIONLRTI BASAL ATELECTASIS Coronary Angiogram was done through radial route on 15/11/22 - PTCA-STENTING TO MID LAD WITH 2.5X28MM(ALPINE) DONE ON LMCA-NORMAL LAD-TYPE III VESSEL, MID tandem lesions with